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RESEARCH PROJECTS

Dr. Chaudhry studies a wide-range of basic and applied biomedical research problems. His research is focused on:

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Embryonic Stem Cell (ESCs), Adult Stem cells (ASCs), Perinatal stem cells (PSCs) and Induced Pluripotent Stem Cells (IPSCs); cellular development and differentiation; Tissue engineering and regeneration; Biotechnology and toxicology.

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Isolation and Characterization of Stem Cells from Perinatal Sources. 

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Development of Three-Dimensional Culture Systems for Maintenance and Expansion of Stem Cells.

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Regulation of Self-Renewal and Differentiation of ESCs, ASCs, PSCs and iPSCs. 

 

Computational Analysis of High-Throughput Sequencing to Determine Genetic and Epigenetic Changes During Development and Differentiation.

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Repair of Intervertebral Disc and Spinal Cord Injuries using Stem Cells and their Derivatives.

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Safety and Feasibility of Neural Derivatives of Stem Cells for the Treatment of Retinal Diseases using Animal Models. 

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Development of Cell Therapy Approaches for the Treatment of Neurodegenerative Diseases and Disorders such as Alzheimer's, Parkinson's and Multiple Sclerosis.

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Toxicity Testing of Pharmaceuticals Drugs using ESCs, ASCs, PSCs and iPSCs.

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His research has been funded by various private, state and federal agencies including Beaumont Foundation, William Beaumont Hospital, St. John Providence and National Science Foundation.

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