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RESEARCH PROJECTS

Dr. Chaudhry studies a wide-range of basic and applied biomedical research problems. His research is focused on:

Embryonic Stem Cell (ESCs), Adult Stem cells (ASCs), Perinatal stem cells (PSCs) and Induced Pluripotent Stem Cells (IPSCs); cellular development and differentiation; Tissue engineering and regeneration; Biotechnology and toxicology.

Isolation and Characterization of Stem Cells from Perinatal Sources. 

Development of Three-Dimensional Culture Systems for Maintenance and Expansion of Stem Cells.

Regulation of Self-Renewal and Differentiation of ESCs, ASCs, PSCs and iPSCs. 

 

Computational Analysis of High-Throughput Sequencing to Determine Genetic and Epigenetic Changes During Development and Differentiation.

Repair of Intervertebral Disc and Spinal Cord Injuries using Stem Cells and their Derivatives.

Safety and Feasibility of Neural Derivatives of Stem Cells for the Treatment of Retinal Diseases using Animal Models. 

Development of Cell Therapy Approaches for the Treatment of Neurodegenerative Diseases and Disorders such as Alzheimer's, Parkinson's and Multiple Sclerosis.

Toxicity Testing of Pharmaceuticals Drugs using ESCs, ASCs, PSCs and iPSCs.

His research has been funded by various private, state and federal agencies including Beaumont Foundation, William Beaumont Hospital, St. John Providence and National Science Foundation.

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